开展

治疗学是一种突破性的精准医学方法. By combining targeted imaging (PET scan) with targeted therapy (radionuclide therapy) using the same molecular target, 它治疗某些类型的晚期癌症.

什么是治疗学?

开展 is a form of precision medicine that combines radioactive materials (radioisotopes) with molecules designed to target cancer cells. 通过将放射性同位素附着在癌症靶向分子上, 皇冠hga025大学洛杉矶分校健康 physicians are able to see where the cancer is 和 then deliver therapeutic radiation directly to it.

By combining small amounts of radioactive material with cancer-targeting molecules, 核医学医生能够诊断, 阶段, 并治疗某些类型的癌症. 这种治疗学和诊断学的结合被称为治疗学.

Clinicians 和 scientists at the 皇冠hga025大学洛杉矶分校健康开展 Center leverage state-of-the-art technology 和 cutting-edge research to bring innovative 和 effective theranostic cancer treatments to our patients.

治疗学是如何工作的?

Certain radioisotopes emit radiation which is not harmful to cells 和 can be imaged using positron emission tomography (PET). 这是治疗学的诊断部分. 另一些则会释放出能破坏甚至杀死细胞的辐射. 这是治疗的部分.

成像

治疗

在开展, doctors administer a specialized molecule called a radiotracer that can hold a radioisotope 和 target cancer cells. 然后放射性示踪剂与癌细胞结合, allowing doctors to see exactly where it is 和 deliver cell-damaging radiation directly to it. 这种“看你治疗什么”的方法有助于医生诊断, 阶段, 在治疗癌症的同时尽量减少对健康组织的损害.

在此之前和期间，你能期待什么 & 经过影像学检查和治疗?

治疗前影像学及治疗:

在开始治疗前进行影像学检查和治疗, you will have a consultation with a 皇冠hga025大学洛杉矶分校健康核医学 physician who will define treatment eligibility 和 explain side effects 和 effects of treatment. 除了你的咨询，你应该:

激活myUCLAhealth (MyChart) 账户
下载MyChart应用到你的智能手机上
阅读医疗团队提供的教育材料
如有任何问题，请联系皇冠hga025大学洛杉矶分校治疗学护理团队
Attend all appointments 和 screening tests to prepare for theranostics imaging 和 therapy
确定一个联系人和一个备用联系人
与您的医疗保健提供者一起查看同意书
Identify transportation for your commute from the Outpatient 开展 Center as you may receive anti-恶心想吐 medication that can make you drowsy

在影像学和治疗过程中:

开展 is performed in an outpatient setting 和 consists of imaging (diagnostic) 和 therapy phases separated by several weeks. Two types of radiotracers are used: an imaging radiotracer which contains a radioisotope that can be imaged with PET, 和 a therapeutic radiotracer which contains a radioisotope that emits cell-damaging radiation. 在整个过程中，您的安全将是我们最关心的.

诊断阶段:观察肿瘤的位置, an imaging radiotracer will be administered by your health care team in our outpatient clinic. You will then undergo a full-body PET scan which will create pictures showing where the radiotracer goes. The whole process typically takes less than 3 hours, after which you can leave the clinic.
治疗阶段:治疗在诊断阶段发现的癌症, your health care team will administer a therapeutic radiotracer in our outpatient clinic. 后管理, 您将由您的护理团队密切监测两到三个小时, 之后你就可以离开诊所了. 治疗周期的长短取决于所治疗的疾病, 但可以从一到六.

经影像学及治疗后:

一旦使用了放射性示踪剂, the cancer-targeting molecule will bind to the cancer before being naturally cleared from your body over the course of several days. 在接受治疗治疗时, the therapeutic radiotracer will deliver cell-damaging radiation directly to the cancer cells until it is naturally cleared.

完成所有治疗周期后, your health care team may perform another PET scan to monitor how the cancer has responded to the treatment.

皇冠hga025大学洛杉矶分校医疗中心提供什么样的治疗疗法?

在皇冠hga025大学洛杉矶分校健康门诊治疗中心, 我们为许多适应症提供最先进的治疗疗法.

前列腺癌: PLUVICTO 和 XOFIGO
神经内分泌肿瘤: Lutathera
甲状腺癌和格雷夫斯病: 意大利广播电视公司(放射性 ¹³¹碘)

病人资源

皇冠hga025

For more information about theranostics imaging 和 therapy at 皇冠hga025大学洛杉矶分校健康, please call 310-794-1005.

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特色文章链接

皇冠hga025大学洛杉矶分校健康 earns Comprehensive Center of Excellence designation for radiopharmaceutical therapy as work continues on new facility

放射治疗被证明是前列腺癌医生的答案

PSMA PET显像提高预测前列腺癌复发的准确性

月球研究

皇冠hga025大学洛杉矶分校健康 earns Comprehensive Center of Excellence designation for radiopharmaceutical therapy as work continues on new facility

FDA批准mCRPC新的放射配体治疗和诊断

前列腺癌的智能炸弹

治疗:泌尿生殖系统癌症- PDF

皇冠hga025大学洛杉矶分校健康约翰逊综合癌症中心

影像学和治疗的副作用

The most common side effect of theranostics imaging is claustrophobia during the full-body PET scan, 而理疗疗法可能伴随着疲劳, 便秘或腹泻, 口干, 恶心想吐, 贫血(红细胞计数低于正常), 还有骨痛. Less common side effects of theranostics therapy include decreases in cells that help fight infection.

因为副作用会因治疗的疾病而异, it is important to consult with your theranostics care team prior to receiving treatment.

谁是治疗学的候选人?

某些前列腺癌患者可以接受治疗, 神经内分泌肿瘤(网), 甲状腺癌, 或格雷夫斯病. 诊断后, your oncologist may refer you to the 皇冠hga025大学洛杉矶分校健康开展 care team for a consultation to determine whether you are a c和idate for theranostics therapy.

为什么选择UCLA健康中心进行治疗治疗?

当你选择皇冠hga025大学洛杉矶分校健康中心进行治疗治疗时，你将得到很好的帮助. Whether at our state-of-the-art Outpatient 开展 Center or through our field-leading research in the laboratory 和 clinic, 我们的医生团队, 研究人员, 员工们专注于为病人提供最好的护理,

开创性临床试验: 皇冠hga025大学洛杉矶分校健康开展 physicians help bring innovative 和 effective treatments to 皇冠hga025大学洛杉矶分校健康 patients by leading 和 participating in pioneering theranostics-based clinical trials such as NCT02940262. 这些研究获得了FDA的批准, 医疗保险报销状况, 和 inclusion in the prostate cancer management guidelines by the National Comprehensive Cancer Network (NCCN). The team led the Phase II RESIST-PC clinical trial to establish the safety 和 efficacy of Pluvicto (¹⁷⁷lupsma -617)治疗转移性去势抵抗性前列腺癌, 和 participated in the pivotal Phase III VISION clinical trial which further demonstrated the efficacy of Pluvicto against metastatic castration-resistant prostate cancer. Based on the positive results of this study, the FDA approved Pluvicto for use in the United States.
经验和专业知识: 自2022年以来, our team has administered over 430 cycles of theranostics therapy to patients with metastatic castration-resistant prostate cancer, 网, 甲状腺癌, 和格雷夫斯病.
开展研究: UCLA is home to one of the premier theranostics research programs in the United States. Our 研究人员和 clinicians collaborate closely to ensure that novel discoveries in the laboratory can be translated into meaningful clinical outcomes for patients at 皇冠hga025大学洛杉矶分校健康和 beyond.

点击这里了解更多我们的前沿研究.